A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions

PHASE1CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

February 17, 2017

Primary Completion Date

August 15, 2017

Study Completion Date

August 15, 2017

Conditions
Hereditary Angioedema
Interventions
DRUG

BCX7353

Day 11-18 for Cohort 1, Day 7-14 for Cohort 2, Day 1 for Cohort 3

DRUG

Digoxin

Day 1 of Cohort 1

DRUG

BCX7353 + digoxin

Day 19 of Cohort 1

DRUG

Rosuvastatin

Day 1 of Cohort 2

DRUG

rosuvastatin + BCX7353

Day 15 of Cohort 1

DRUG

Cyclosporine + BCX7353

Day 14 of Cohort 3

Trial Locations (1)

LS2 9LH

Covance CRU, Leeds

Sponsors
All Listed Sponsors
lead

BioCryst Pharmaceuticals

INDUSTRY

NCT03136237 - A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions | Biotech Hunter | Biotech Hunter