AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS)

PHASE2CompletedINTERVENTIONAL
Enrollment

137

Participants

Timeline

Start Date

June 22, 2017

Primary Completion Date

September 25, 2019

Study Completion Date

November 24, 2019

Conditions
Amyotrophic Lateral SclerosisMotor Neuron DiseaseNeuromuscular DiseasesNeurodegenerative DiseasesSpinal Cord DiseasesTDP-43 ProteinopathiesNervous System DiseasesCentral Nervous System Diseases
Interventions
DRUG

AMX0035

AMX0035

OTHER

Placebo

Matching Placebo Comparator

Trial Locations (25)

10003

Mount Sinai Beth Israel, New York

19107

The Penn Comprehensive ALS Center, Philadelphia

19140

Temple University Hospital, Philadelphia

21287

Johns Hopkins Hospital, Baltimore

27157

Wake Forest Baptist Medical Center, Winston-Salem

30322

Emory University Hospital, Atlanta

32610

University of Florida Medical Center, Gainesville

33612

Carol and Frank Morsini Center for Advanced Health Care - University of South Florida, Tampa

40536

University of Kentucky Medical Center, Lexington

43221

The Ohio State University Wexner Medical Center, Columbus

48109

University of Michigan Medical Center, Ann Arbor

52242

University of Iowa Hospitals and Clinics, Iowa City

55415

Hennepin County Medical Center, Minneapolis

63110

Washington University Medical Center, St Louis

68506

Neurology Associates P.C., Lincoln

70121

Ochsner Neuroscience Institute, New Orleans

75214

Texas Neurology, P.A., Dallas

78229

University of Texas Health Science Center at San Antonio, San Antonio

85013

Barrow Neurological Institute, Phoenix

92868

UC Irvine Medical Center, Orange

94114

Forbes Norris MDA/ALS Research Center - California Pacific Medical Center, San Francisco

97239

Oregon Health & Science University, Portland

98122

ALS Center at the Swedish Neuroscience Institute, Seattle

02114

Massachusetts General Hospital, Boston

01655

University of Massachusetts Memorial Medical Center, Worcester

Sponsors
All Listed Sponsors
collaborator

ALS Finding a Cure

OTHER

collaborator

ALS Association

OTHER

collaborator

Northeast ALS Consortium

OTHER

collaborator

Neurological Clinical Research Institute at Massachusetts General Hospital

OTHER

collaborator

Leandro P. Rizzuto Foundation

OTHER

lead

Amylyx Pharmaceuticals Inc.

INDUSTRY

NCT03127514 - AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) | Biotech Hunter | Biotech Hunter