NCT03124355View on ClinicalTrials.gov

Vagal Stimulation in POTS

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

September 30, 2017

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Postural Tachycardia Syndrome
Interventions
DRUG

placebo sugar pill

placebo single oral dose

DRUG

Pyridostigmine Pill

pyridostigmine bromide 30 mg single oral dose

DRUG

Galantamine Pill

Galantamine hydrobromide 8mg single oral dose

DEVICE

Vagal stimulation

Vagal stimulation will be given at 50 Hz during the tilt table tests

DEVICE

Sham vagal stimulation

Sham vagal stimulation will be given at 0.01 mA during the tilt table tests

Trial Locations (1)

37232

Autonomic Dysfunction Center/ Vanderbilt University Medical Center, Nashville

All Listed Sponsors
lead

Vanderbilt University Medical Center

OTHER