Immunotherapy and Stereotactic Body Radiotherapy (SBRT) for Metastatic Anaplastic Thyroid Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

April 25, 2017

Primary Completion Date

June 3, 2022

Study Completion Date

June 3, 2022

Conditions
Metastatic Anaplastic Thyroid Cancer
Interventions
DRUG

durvalumab

Patients will receive durvalumab (MEDI4736) and tremelimumab together every 4 weeks.

DRUG

tremelimumab

Patients will receive durvalumab (MEDI4736) and tremelimumab together every 4 weeks.

RADIATION

Stereotactic Body Radiotherapy (SBRT)

SBRT at 9Gy x 3 per standard of care given within 2 weeks after the completion of Cycle 1 of durvalumab (MEDI4736) and tremelimumab

Trial Locations (8)

10065

Memorial Sloan Kettering Cancer Center, New York

10604

Memoral Sloan Kettering Westchester, Harrison

11553

Memorial Sloan Kettering Nassau, Uniondale

11570

Memorial Sloan Kettering @ Rockville, Rockville Centre

11725

Memorial Sloan Kettering Commack, Commack

07920

Memoral Sloan Kettering Basking Ridge, Basking Ridge

07748

Memoral Sloan Kettering Monmouth, Middletown

07645

Memorial Sloan Kettering Bergen, Montvale

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Memorial Sloan Kettering Cancer Center

OTHER