24
Participants
Start Date
September 11, 2017
Primary Completion Date
November 15, 2017
Study Completion Date
November 15, 2017
10 mg dose MR formulations,10 mg dose of tofacitinib IR solution
"For the the relative bioavailability (BA) assessment , the investigational product(s) are:~Test: 10 mg dose of age-appropriate MR formulations (MR-fast, MR-moderate, MR-slow). Each formulation contains 0.025 mg of tofacitinib/mg of microsphere. Reference: 10 mg dose of tofacitinib IR solution (1 mg of tofacitinib/mL).~For the the food effect assessment, the investigational product(s) are:~Test: 10 mg dose of age-appropriate MR formulations (MR-fast or MR-slow) c-oadministered with high-fat FDA breakfast. Reference: 10 mg dose of age-appropriate MR formulations (MR-fast or MR-slow) administered under fasted state."
Pfizer New Haven Clinical Research Unit, New Haven
Lead Sponsor
Pfizer
INDUSTRY