Role of Metformin on Muscle Health of Older Adults

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

August 1, 2019

Primary Completion Date

November 1, 2025

Study Completion Date

November 1, 2025

Conditions
Muscle AtrophyInsulin Resistance
Interventions
DRUG

Metformin (Bed Rest)

A clinical oral dose of Metformin will be given to participant daily during bed rest

DRUG

Placebo (Bed Rest)

Placebo-comparator. The same quantity of non-active tablets will be given at the same time of day as the Metformin treatment group

DRUG

Metformin (2 week run-in only)

A clinical oral dose of Metformin will be given to participant daily during a two week run-in period only.

DRUG

Placebo (2 week run-in only)

Placebo-comparator. The same quantity of non-active tablets will be given at the same time of day as the Metformin 2 week run-in treatment group.

Trial Locations (1)

84108

University of Utah, Salt Lake City

All Listed Sponsors
lead

University of Utah

OTHER