NCT03105843View on ClinicalTrials.gov

Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol

PHASE4RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

June 1, 2026

Study Completion Date

June 30, 2026

Conditions
AsthmaCoughCough Variant Asthma
Interventions
DRUG

Methacholine (MCh) Challenge Testing

Visit 1: Informed consent, Baseline screening and pulmonary function tests and Low-dose methacholine challenge testing using partial and full flow-volume loops.

DIAGNOSTIC_TEST

Eucapneic Voluntary Hyperventilation (EVH)

Visit 2 or 3: Will be conducted in random order and subjects will perform one of the two challenge tests at either visit.

DRUG

Mannitol Inhalation Kit

Visit 2 or 3: Will be conducted in random order and subjects will perform one of the two challenge tests at either visit.

Trial Locations (1)

K7L 2V7

RECRUITING

Kingston Health Sciences Centre, Kingston

All Listed Sponsors
lead

Dr. Diane Lougheed

OTHER