Evaluating Raised Intracranial Pressure Using MR Elastography

MR elastography image acquisition will be conducted on the Compact 3T MRI scanner using a modified single-shot spin-echo echo-planar imaging pulse sequence.

MRI structural brain imaging will be done on the Compact 3T MRI at the same time as MR elastography.

All patients with papilledema will get lumbar punctures with opening pressure as part of their work-up for papilledema. A small number of patients without increased intracranial pressure will receive a lumbar puncture.

Optical Coherence Tomography (OCT) imaging will measure the peripapillary retinal nerve fiber layer (RNFL) thickness measurements The images with enhanced depth imaging will be obtained to measure the Bruch's membrane orientation.

Ultrasound will be used to measure the optic nerve sheath diameter 3 mm posterior to the posterior scleral surface.