Chemotherapy Combined With CIK Treating Colon Cancer

PHASE4CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

May 6, 2012

Primary Completion Date

September 15, 2014

Study Completion Date

September 15, 2014

Conditions
Cytokine-induced Killer CellsPostoperative ComplicationsSurvivalColorectal Cancer
Interventions
DRUG

Cytokine-induced killer cells+ FOLFOX4

Day 1: Oxaliplatin 130 mg/m² IV infusion in 500 mL D5W. Day 2-6: leucovorin 200mg/m² IV infusion in D5W both given over 2 hours at the same time in separate bags Day 2-6: 5-FU 500 mg/m² IV bolus given continuously over 4-6 hours. The treatment is given for 4-6 cycles, every 3 weeks. Collected CIK cells were suspended with 100ml saline (containing 5ml 20% human serum albumin) and given continuously over 2 hours/ day for 3 days.

DRUG

FOLFOX4

Day 1: Oxaliplatin 130 mg/m² IV infusion in 500 mL D5W. Day 2-6: leucovorin 200mg/m² IV infusion in D5W both given over 2 hours at the same time in separate bags Day 2-6: 5-FU 500 mg/m² IV bolus given continuously over 4-6 hours. The treatment is given for 4-6 cycles, every 3 weeks.

All Listed Sponsors
lead

China Meitan General Hospital

OTHER

NCT03084809 - Chemotherapy Combined With CIK Treating Colon Cancer | Biotech Hunter | Biotech Hunter