Afatinib in Locally Advanced and Metastatic Chordoma

PHASE2CompletedINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

June 21, 2018

Primary Completion Date

January 31, 2025

Study Completion Date

January 31, 2025

Conditions
Chordoma
Interventions
DRUG

Afatinib

Afatinib will be given daily in a dose of 40 mg orally in a 4 week cycle until disease progression or patient withdrawal.

Trial Locations (3)

Unknown

Istituto Nazionale dei Tumori: Fondazione IRCCS, Milan

Leiden University Medical Center, Leiden

University College London Hospital, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Chordoma Foundation

OTHER

collaborator

Boehringer Ingelheim

INDUSTRY

lead

Leiden University Medical Center

OTHER