1,250
Participants
Start Date
December 1, 2016
Primary Completion Date
December 30, 2019
Study Completion Date
June 20, 2020
FullPIERS and sFlit/PLGF (Soluble fms-Like Tyrosine Kinase-1-to-Placental Growth Factor Ratio)
Once the centre is randomised to receive the intervention, all eligible women will have serum sFlt1/PlGF measurement performed and fullPIERS assessment and both results will be revealed to the care providers. This will include all women with pre-eclampsia or suspected pre-eclampsia cared for at the main hospital centres (and not be limited to women referred to the hospital from the community health centres). sFlt-1/PlGF will be tested by immunoassays (Roche Platform®). The result read out is provided by specific machines provided by Roche in less than one hour, which permits rapid clinical decision-making. Risk stratification using fullPIERS will be performed on tablet computers using a pre-defined risk scoring system integrated within the MedSciNet database.
Instituto Fernandes Figueira, Rio de Janeiro
Hospital de Clinicas de Porto Alegre, Porto Alegre
Maternidade Unesp Botucatu, Botucatu
Caism - Unicamp, Campinas
Hospital Guilherme Alvaro, Santos
Maternidade Maria Amelia Buarque de Holanda, Rio de Janeiro
Maternidade Leila Diniz, Rio de Janeiro
Hospital Maternidade Leonor Mendes de Barros, São Paulo
Instituto Fernandes Figueira
OTHER_GOV
CoLab
UNKNOWN
SMSDC/RJ
UNKNOWN
University of Campinas, Brazil
OTHER
UPECLIN HC FM Botucatu Unesp
OTHER
HGA
UNKNOWN
HOSPITAL MATERNIDADE LEONOR MENDES DE BARROS
UNKNOWN
Hospital de Clinicas de Porto Alegre
OTHER