14
Participants
Start Date
August 1, 2017
Primary Completion Date
April 7, 2021
Study Completion Date
October 30, 2023
Blinatumomab
-Blinatumomab is a bispecific T cell engaging antibody
Autologous stem cell transplant
-Standard of care
Carmustine
-Carmustine is an alkylating agent. It will be sourced from commercial supply. Institutional guidelines will be followed for storage, preparation, and administration of carmustine.
Etoposide
-Etoposide is a semi-synthetic podophyllotoxin derivative. It will be sourced from commercial supply. Institutional guidelines will be followed for storage, preparation, and administration of etoposide.
Cytarabine
-Cytarabine, commonly known as Ara-C, is a synthetic nucleoside. It will be sourced from commercial supply. Institutional guidelines will be followed for storage, preparation, and administration of cytarabine.
Melphalan
-Melphalan is an alkylating agent. It will be sourced from commercial supply. Institutional guidelines will be followed for storage, preparation, and administration of melphalan.
Peripheral blood draws
-Day +42, Day + 43, Day +56, and Day +100
Washington University School of Medicine, St Louis
Collaborators (1)
Amgen
INDUSTRY
Washington University School of Medicine
OTHER