Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF

NAActive, not recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

February 1, 2017

Primary Completion Date

May 31, 2028

Study Completion Date

May 31, 2029

Conditions
Acquired Aplastic AnemiaParoxysmal Nocturnal HemoglobinuriaInherited Bone Marrow Failure Syndromes
Interventions
DEVICE

CliniMACs

Peripheral blood stem cells from closely matched unrelated or partially matched related donors will be processed using the CliniMACS device to remove TCRalpha/beta T cells and B cells, in accordance with the Investigator Brochure and Technical Manual following the laboratory standard operating procedures (SOPs) and using aseptic technique

Trial Locations (1)

19104

Children's Hospital of Philadelphia, Philadelphia

All Listed Sponsors
lead

Children's Hospital of Philadelphia

OTHER

NCT03047746 - Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF | Biotech Hunter | Biotech Hunter