Impact of Liraglutide 3.0 on Body Fat Distribution

PHASE4CompletedINTERVENTIONAL
Enrollment

235

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

October 13, 2020

Study Completion Date

October 13, 2020

Conditions
Obesity, VisceralCardiovascular DiseasesFat Disorder
Interventions
DRUG

Liraglutide

Liraglutide is administered once daily by subcutaneous injections with the pen-injector, either in the abdomen, thigh or upper arm. Injections can be done at any time of day irrespective of meals. Subjects will be instructed to escalate the liraglutide dose to 3.0 mg/day over a 4 week period following an initial dose of 0.6 mg/day and weekly dose escalation steps of 0.6 mg/day.

DRUG

Placebo

Placebo is administered once daily by subcutaneous injections with the pen-injector, either in the abdomen, thigh or upper arm. Injections can be done at any time of day irrespective of meals. Subjects will be instructed to escalate the placebo dose to 3.0 mg/day over a 4 week period following an initial dose of 0.6 mg/day and weekly dose escalation steps of 0.6 mg/day.

Trial Locations (1)

75390

University of Texas Southwestern Medical Center, Dallas

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novo Nordisk A/S

INDUSTRY

lead

University of Texas Southwestern Medical Center

OTHER