NCT03033329 - Single Dose Escalation and Multiple Dose Escalation Trial of an Intravenous Formulation of MRX-4 | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 31, 2016

Primary Completion Date

March 31, 2018

Study Completion Date

March 31, 2018

Conditions

Safety

Interventions

DRUG

Single intravenous doses of MRX-4

Intravenous single escalating doses of MRX-4

DRUG

Single intravenous doses of placebo

Intravenous single doses of placebo to match MRX-4

DRUG

Multiple intravenous doses of MRX-4

Multiple ascending doses of MRX-4 given intravenously twice daily for 10 days

DRUG

Multiple intravenous doses of placebo

Multiple doses of placebo to match MRX-4 given intravenously twice daily for 10 days

DRUG

Single dose of intravenous and oral MRX-4

Crossover single dose of intravenous and oral MRX-4 given on Day 1 and Day 4