31
Participants
Start Date
June 29, 2017
Primary Completion Date
June 24, 2024
Study Completion Date
June 24, 2024
Atezolizumab
Atezolizumab will be given intravenously every 3 weeks at 1200 mg.
Bevacizumab
Bevacizumab will be given intravenously every 3 weeks at 15 mg/kg.
Entinostat
Entinostat will be given orally every 7 days at 1, 3, or 5 mg depending upon phase. In Phase I, dose levels will be tested in up to 3 cohorts starting at 1 mg. In Phase II, the dose will be the recommended phase II dose that was determined during Phase I (i.e., 1, 3, or 5 mg).
University of Pennsylvania, Philadelphia
Ohio State University, Columbus
Indiana University Health Hospital, Indianapolis
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis
Collaborators (2)
Genentech, Inc.
INDUSTRY
Syndax Pharmaceuticals
INDUSTRY
Roberto Pili
OTHER