Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

187

Participants

Timeline

Start Date

March 7, 2017

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Charcot-Marie-Tooth Disease, Type IA
Interventions
DRUG

PXT3003

Liquid oral solution, twice 5 mL (Dose 1) bid

Trial Locations (23)

10032

Peripheral Neuropathy Center, Neurological Institue Building, Columbia University Medical Center, New York

32610

Department of Neurology, McKnight Brain Institute, Gainesville

55455

Department of Neurology, University of Minnesota, Minneapolis

66160

University of Kansas Medical Center, Kansas City

90048

Department of Neurology, Cedars-Sinai Medical Center, Los Angeles

02115

Brigham and Women's Hospital, Boston

48109-5322

University of Michigan Health System, Ann Arbor

63104-1027

Department of Neurology and Psichiatry, Saint Louis University, St Louis

99202-1330

Saint Luke's Rehabilitation Institute, Spokane

Unknown

Departement of Neurology, UZ Leuven, Leuven

Cntre de Reference des Maladies Neuromusculaires, Hopital Swynghedauwl, CHU Lille, Lille

Centre de Reference des Neuropathies Peripheriques Rare, Hopital Dupuytren, CHU Limoges, Limoges

Service de Neurologie et du Sommeil, CHU Lyon Sud, Lyon

Centre de Reference des Maladie Neuromusculaires, CHU la Timone, Marseille

Centre de Reference des Maladie Neuromusculaires, Hotel Dieu, CHU de Nantes, Nantes

Service de Neurologie, Hopital Kremlin Bicetre, Paris

Departement of Neurology, Academic Medical Center, Amsterdam

Department of neurology, Hospital Univesitario de Bellvitge, Barcelona

Servicio de Neurologia, Hospital Universitario La Paz, Madrid

Centro de Diagnostico y Tratamiento, Hospital Universitario Virgen del Rocio, Seville

Servicio de Neurologia, Hospital Universitario i Politécnic La Fe, Valencia

G1J 1Z4

University Hospital of Quebec, Québec

M6 8HD

Department of Neurology, Salford Royal NHS Foundation Trust, Salford

All Listed Sponsors
collaborator

Synteract HCR (Syneos Health)

UNKNOWN

collaborator

Premier Research Group plc

UNKNOWN

collaborator

Greenphire

UNKNOWN

collaborator

Theradis

UNKNOWN

collaborator

Amarex

UNKNOWN

collaborator

Eurofins Optimed

INDUSTRY

lead

Pharnext S.C.A.

OTHER