Study of Niraparib and TSR-042 in Recurrent Endometrial Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

November 6, 2017

Primary Completion Date

January 5, 2021

Study Completion Date

December 31, 2025

Conditions
Endometrial Cancer
Interventions
DRUG

Niraparib

200 or 300 mg daily PO, for 21 day cycle

DRUG

TSR-042

500 mg once intravenously on day 1 of cycle (From cycle 1-4 followed by 1000 mg intravenously every 6 weeks for maximum of 2 yrs)

Trial Locations (7)

T2N 4N2

Tom Baker Cancer Centre, Calgary

L8V 5C2

Juravinski Cancer Centre, Hamilton

K7L 5P9

Cancer Centre of Southeastern Ontario at Kingston, Kingston

N6A 4L6

London Regional Cancer Centre, London

M4N 3M5

Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto

M5G 1M9

Princess Margaret Cancer Centre, Toronto

H3A 3J1

McGill University Health Centre - Glen Site, Montreal

All Listed Sponsors
collaborator

Tesaro, Inc.

INDUSTRY

lead

University Health Network, Toronto

OTHER