Interstitial Cystitis: Examination of the Central Autonomic Network

PHASE4CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

March 1, 2017

Primary Completion Date

March 16, 2022

Study Completion Date

March 16, 2022

Conditions
Interstitial Cystitis/Painful Bladder SyndromeMyofascial Pelvic Pain
Interventions
DRUG

Metoprolol Tartrate Oral Tablet

Metoprolol is a beta-blocker commonly used for mild blood pressure control, and also commonly used for migraine. Subjects with IC/BPS or MPP will start metoprolol at 25 mg once daily and increase to the goal dose of 25 mg 2/day after one week and continue for 8 weeks total.

DRUG

Placebo Oral Tablet

Subjects with IC/BPS or MPP will start placebo distributed in a double-blind manner. Subjects will take placebo once daily and increase to the goal dose of 25 mg 2/day after one week and continue for 8 weeks total.

OTHER

No intervention- observational sub-study

Participants did not receive placebo or metoprolol during the entire duration of the study.

Trial Locations (2)

23298

Virginia Commonwealth University, Richmond

60201

NorthShore University HealthSystem, Evanston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Endeavor Health

OTHER

collaborator

Case Western Reserve University

OTHER

lead

Virginia Commonwealth University

OTHER