NCT03004118View on ClinicalTrials.gov

Therapeutic Effect of Ursodeoxycholic Acid in Functional Dyspepsia

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Functional Dyspepsia
Interventions
DIETARY_SUPPLEMENT

Nutridrink

Liquid meal of 200ml

DEVICE

High resolution manometry probe

Catheter inserted via the nose into the stomach to measure intragastric pressure.

DEVICE

perfusion catheter

Catheter inserted via the nose into the stomach to perfuse the nutridrink intragastricly.

DRUG

Placebo Oral Tablet

4 week oral intake (daily)

DRUG

Ursochol oral tablet

4 week oral intake (daily) (dose of 10.5mg/kg/day)

DEVICE

Duodenal fluid aspiration catheter

Catheter inserted via the nose into the duodenum to aspirate duodenal fluids for 2.5 hours.

PROCEDURE

Duodenogastroscopy

Catheter inserted via the mounth into the duodenum to take duodenal biopsies.

PROCEDURE

Blood sample

Blood sample will be taken to measure liver enzyme serum levels and marker for bile acid synthesis.

All Listed Sponsors
lead

Universitaire Ziekenhuizen KU Leuven

OTHER