13
Participants
Start Date
September 30, 2011
Primary Completion Date
December 31, 2012
Study Completion Date
December 31, 2012
PET Scans
Two 90 minute scans whose maximum radiological dose is 15 mCi \[11 C\] carfentanil, a selective and specific mu-opioid receptor radioligand. The first one provided baseline data, and the second occurred with the sequence of sham tDCS and tDCS as described in each arm description.
transcranial direct current stimulation (tDCS)
In active tDCS, a 2 milli-amp transcranial direct current stimulation is for 20 minutes.
MRI
No radiotracer is used; 3 tesla scanner; all participants have MRI prior to PET scans.
sham tDCS (prior to real tDCS)
For sham tDCS, current is applied only for 30 seconds, as sensations arising from tDCS treatment occur only at the beginning of application; however the equipment will be on the participant for 20 minutes to match that of the active tDCS application.
University of Michigan, Ann Arbor
University of Michigan
OTHER