Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension

PHASE2/PHASE3TerminatedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

September 28, 2017

Primary Completion Date

May 4, 2023

Study Completion Date

November 1, 2023

Conditions
Hypertension,Pulmonary
Interventions
BIOLOGICAL

Placebo followed by Autologous EPCs transfected with human eNOS

4 doses of placebo in first 6 months followed by 4 doses of autologous EPCs transfected with eNOS in second 6 months

BIOLOGICAL

Autologous EPCs transfected with human eNOS followed by Placebo

4 doses of autologous EPCs transfected with eNOS in first 6 months followed by 4 doses of placebo in second 6 months

BIOLOGICAL

Autologous EPCs transfected with human eNOS

4 doses of autologous EPCs transfected with eNOS in first 6 months which is repeated in second 6 months

Trial Locations (4)

T1Y 6J4

Peter Lougheed Center, University of Calgary, Calgary

N6A 5W9

London Health Sciences Center, London

K1Y 4W7

University of Ottawa Heart Institute, Ottawa

M5G 2N2

Toronto General Hospital, Toronto

Sponsors
All Listed Sponsors
collaborator

Ottawa Hospital Research Institute

OTHER

lead

Northern Therapeutics

INDUSTRY