A Randomized Controlled Trial Comparing Chondro-Gide® to Microfracture Alone for Treatment of Knee Cartilage Defects.

PHASE3CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

December 31, 2003

Primary Completion Date

December 31, 2015

Study Completion Date

July 31, 2016

Conditions
Cartilage InjuryOsteochondritis Dissecans
Interventions
PROCEDURE

Microfracture

Microfracture is a well-established arthroscopic surgical technique for cartilage repair which involves several systematic steps, including debridement to a stable cartilage margin, careful removal of the calcified cartilage layer, and homogeneous placement of microfracture penetrations within the cartilage defect, with resultant complete defect fill by a well-anchored clot

DEVICE

Chondro-Gide sutured

Implantation of Chondro-Gide membrane using atraumatic sutures following microfracture via mini-arthrotomy

DEVICE

Chondro-Gide glued

Implantation of Chondro-Gide membrane using Fibrin glue following microfracture via mini-arthrotomy

Trial Locations (7)

Unknown

University of Regensburg, Bad Abbach

Universitätsklinikum Freiburg, Freiburg im Breisgau

Universitätsklinikum Giessen, Giessen

Orthopedikum Hamburg, Hamburg

Unfallklinik Hannover, Hanover

University of Schleswig-Holstein, Lübeck

Sportklinik Ravensburg, Ravensburg

Sponsors
All Listed Sponsors
lead

Geistlich Pharma AG

INDUSTRY