NATIENS: Optimal Management and Mechanisms of SJS/TEN

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

March 21, 2023

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Stevens-Johnson SyndromeToxic Epidermal Necrolyses
Interventions
DRUG

Harmonized supportive care

Harmonized supportive care with and etanercept placebo days 1 and 4

DRUG

Etanercept 50 mg sc day 1 and day 4

Harmonized supportive care with placebo

Trial Locations (14)

20010

MedStar Washington Hospital Center, Washington D.C.

21224

Johns Hopkins Bayview Medical Center, Baltimore

30303

Emory University at Grady Memorial Hospital, Atlanta

32610

University of Florida Health Burn Center, Gainesville

33136

University of Miami, Ryder Trauma Center, Miami

37232

Vanderblt University Medical Center, Nashville

38103

University of Tennessee Health Sciences Center, Memphis

48201

Wayne State University, Detroit

60153

Loyola University Medical Center, Maywood

75390

University of Texas Southwestern Medical Center, Dallas

77555

University of Texas Medical Branch, Galveston

85008

Valleywise Health Medical Center, Phoenix

95817

University of California, Davis Medical Center, Sacramento

98104

University of Washington, Harborview Medical Center, Seattle

All Listed Sponsors
collaborator

University of Ottawa

OTHER

collaborator

University of Toronto

OTHER

lead

Vanderbilt University Medical Center

OTHER