Evaluation of the Effect of 3HP vs Periodic 3HP vs 6H in HIV-Positive Individuals

PHASE3CompletedINTERVENTIONAL
Enrollment

4,027

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

October 18, 2019

Study Completion Date

October 18, 2019

Conditions
TuberculosisHIV
Interventions
DRUG

rifapentine + isoniazid

Rifapentine + isoniazid Once weekly rifapentine (at a dose of 900 mg) plus isoniazid (at a dose of 900 mg), with adjustment for participants weighing ≤50 kg

DRUG

Isoniazid

Daily self-administered isoniazid (at a dose of 300 mg/daily), with adjustment for participants weighing ≤24 kg

Trial Locations (1)

2193

The Aurum Institute NPC, Johannesburg

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Aurum Institute

OTHER

collaborator

London School of Hygiene and Tropical Medicine

OTHER

collaborator

Johns Hopkins University

OTHER

lead

The Aurum Institute NPC

OTHER