A Biomarker Study in Advanced Mucosal or Acral Lentiginous Melanoma Receiving Nivolumab in Combination With Ipilimumab

PHASE2TerminatedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

July 26, 2017

Primary Completion Date

July 28, 2020

Study Completion Date

August 2, 2022

Conditions
Acral Lentiginous MelanomaMucosal Melanoma
Interventions
DRUG

Nivolumab

nivolumab administered IV over 60 minutes at 1 mg/kg every 3 weeks for 4 treatment cycles (Induction) then continue with nivolumab administered IV over 60 minutes at 3 mg/kg every 2 weeks

DRUG

Ipilimumab

ipilimumab administered IV over 90 minutes at 3 mg/kg every 3 weeks for 4 treatment cycles (Induction)

Trial Locations (5)

10065

Memorial Sloan Kettering Cancer Center, New York

20007

Lombardi Comprehensive Cancer Center, Washington D.C.

20010

Washington Cancer Institute at MedStar Washington Hospital Center, Washington D.C.

33612

H. Lee Moffitt Cancer Center and Research Institute, Tampa

07601

John Theurer Cacner Center at Hackensack University Medical Center, Hackensack

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Melanoma Research Foundation Breakthrough Consortium

OTHER

collaborator

Bristol-Myers Squibb

INDUSTRY

collaborator

University of Colorado, Denver

OTHER

collaborator

University of California, San Francisco

OTHER

collaborator

Vanderbilt University

OTHER

collaborator

Columbia University

OTHER

collaborator

University of Pittsburgh

OTHER

collaborator

Yale University

OTHER

collaborator

M.D. Anderson Cancer Center

OTHER

collaborator

H. Lee Moffitt Cancer Center and Research Institute

OTHER

collaborator

Memorial Sloan Kettering Cancer Center

OTHER

collaborator

Northwestern University

OTHER

collaborator

Dana-Farber Cancer Institute

OTHER

lead

Georgetown University

OTHER