Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy

PHASE3CompletedINTERVENTIONAL
Enrollment

149

Participants

Timeline

Start Date

May 4, 2017

Primary Completion Date

July 27, 2020

Study Completion Date

August 2, 2022

Conditions
PolymyositisDermatomyositisAutoimmune Necrotizing MyopathyOverlap MyositisJuvenile Myositis Above the Age of 18
Interventions
DRUG

Abatacept subcutaneous

Specified dose of Abatacept subcutaneous on specified days

DRUG

Placebo

Placebo of Abatacept subcutaneous

Trial Locations (79)

2050

Local Institution - 0051, Camperdown

2065

Local Institution - 0053, St Leonards

4066

Local Institution - 0035, Auchenflower

6150

Local Institution - 0036, Murdoch

10021

Local Institution - 0097, New York

10117

Local Institution - 0027, Berlin

11850

Local Institution - 0046, Mexico City

15213

Local Institution - 0014, Pittsburgh

17176

Local Institution - 0037, Stockholm

18015

Local Institution - 0055, Bethlehem

20037

Local Institution - 0057, Washington D.C.

21224

Johns Hopkins University -Johns Hopkins Bayview Medical Center, Baltimore

22242

Local Institution - 0040, Lund

22763

Local Institution - 0028, Hamburg

27100

Local Institution - 0023, Pavia

28401

Local Institution - 0010, Wilmington

29118

Local Institution - 0005, Orangeburg

29200

Local Institution - 0100, Brest

33136

Local Institution - 0013, Miami

33309

Local Institution - 0018, Fort Lauderdale

35128

Local Institution - 0020, Padua

38305

Local Institution - 0017, Jackson

43203

Local Institution - 0056, Columbus

44124

Local Institution - 0031, Ferrara

44130

Local Institution - 0094, Middleburg Heights

44160

Local Institution - 0048, Guadalajara

48109

Local Institution - 0089, Ann Arbor

50139

Local Institution - 0024, Florence

55121

Local Institution - 0002, Eagan

56126

Local Institution - 0025, Pisa

59037

Local Institution - 0043, Lille

63000

Local Institution - 0045, Clermont-Ferrand

66160

Local Institution - 0006, Kansas City

67098

Local Institution - 0044, Strasbourg

70185

Local Institution - 0041, Örebro

72189

Local Institution - 0038, Västerås

73072

Local Institution - 0059, Norman

75651

Local Institution - 0042, Paris

77030

Local Institution - 0016, Houston

78213

Local Institution - 0047, San Luis Potosí City

78290

Local Institution - 0052, San Luis Potosí City

78756

Local Institution - 0096, Austin

80336

Local Institution - 0030, München

85028

Local Institution - 0015, Phoenix

90211

Local Institution - 0075, Beverly Hills

92868

Local Institution - 0012, Orange

98195

Local Institution - 0095, Seattle

1138603

Local Institution - 0079, Bunkyo-ku

1608582

Local Institution - 0092, Shinjuku-ku

1628666

Local Institution - 0093, Shinjuku-Ku

2168511

Local Institution - 0083, Kawasaki-shi

3058576

Local Institution - 0082, Tsukuba

3500495

Local Institution - 0077, Iruma-gun

8528501

Local Institution - 0088, Nagasaki

8608556

Local Institution - 0084, Kumamoto

36010570

Local Institution - 0069, Juiz de Fora

40150150

Local Institution - 0073, Salvador

02115

Local Institution - 0058, Boston

68198-3025

Local Institution - 0011, Omaha

03756

Local Institution - 0004, Lebanon

29055-450

Local Institution - 0070, Vitória

90480-000

Local Institution - 0072, Porto Alegre

09090-790

Local Institution - 0074, Bairro Jardim

90035-000

Local Institution - 0067, Rio Grande

04032-060

Local Institution - 0071, São Paulo

128 50

Local Institution - 0029, Prague

06120

Local Institution - 0054, Halle

807-8555

Local Institution - 0091, Kitakyushu

060-0011

Local Institution - 0090, Sapporo

060-8648

Local Institution - 0078, Sapporo

857-1195

Local Institution, Sasebo

113-8519

Local Institution - 0086, Bunkyo-ku

104-8560

Local Institution - 0081, Chuo-ku

755-8505

Local Institution - 0087, Ube-shi

980-8574

Local Institution - 0076, Miyagi

06700

Local Institution - 0049, Mexico City

02447

Local Institution - 0066, Seoul

03080

Local Institution - 0065, Seoul

04763

Local Institution - 0064, Seoul

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY