27
Participants
Start Date
April 25, 2017
Primary Completion Date
March 26, 2019
Study Completion Date
October 31, 2025
Pembrolizumab
Pembrolizumab: 200 mg every 3 weeks, 12 doses planned. This is considered the investigational part of the combination. The infusion time is 1 hour.
Interleukin-2
Interleukin-2: 8 admissions to hospital, each with 5 doses planned. This is considered the standard part of the combination. The standard interleukin-2 dose is 600,000 international units per kilogram per dose, with a maximum of 66,000,000 (for patients over 110 kg, which is 242 pounds). The dose is usually set at the start of the treatment and not adjusted. The infusion time is 15 minutes.
H. Lee Moffitt Cancer Center and Research Institute, Tampa
Collaborators (1)
Merck Sharp & Dohme LLC
INDUSTRY
Prometheus Laboratories
INDUSTRY
H. Lee Moffitt Cancer Center and Research Institute
OTHER