Immunogenicity of Twice-annual Influenza Vaccination in Older Adults in Hong Kong

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

November 18, 2016

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2026

Conditions
Influenza, Human
Interventions
BIOLOGICAL

Inactivated influenza vaccine (NH formulation)

Round 1 (November): 0.5mL FluQuadri®, Sanofi Pasteur, containing 60μg antigen - 15μg for each influenza strain included - with strains recommended by the WHO for the northern hemisphere formulation

BIOLOGICAL

Inactivated influenza vaccine (SH formulation)

Round 2 (May): 0.5mL Vaxigrip®, Sanofi Pasteur, containing 45μg antigen - 15μg for each influenza strain included - with strains recommended by the WHO for the southern hemisphere formulation

BIOLOGICAL

Placebo

Round 2 (May): 0.5mL normal saline

Trial Locations (1)

Unknown

The University of Hong Kong, Hong Kong

All Listed Sponsors
collaborator

Centers for Disease Control and Prevention

FED

collaborator

Hospital Authority, Hong Kong

OTHER_GOV

lead

The University of Hong Kong

OTHER