A Study to Assess the Safety, Tolerability and Potential Efficacy of a Tracheal Replacement Consisting of a Tissue-engineered Tracheal Scaffold With Seeded Mesenchymal Cells

PHASE1SuspendedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

September 30, 2016

Primary Completion Date

September 30, 2019

Study Completion Date

September 30, 2024

Conditions

TracheomalaciaTracheal Stenosis

Interventions

PROCEDURE

Cadaveric decellularised tracheal scaffold seeded with autologous mesenchymal cells

The tracheal graft will be manufactured from cadaveric tracheal scaffold and bone marrow derived mesenchymal cells.

Trial Locations (1)

Royal Nose Throat and Ear Institute, London