A MAD Study of TT301/MW189 in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

March 20, 2017

Primary Completion Date

June 4, 2018

Study Completion Date

June 4, 2018

Conditions
Healthy Adult Volunteers
Interventions
DRUG

0.075mg/kg TT301/MW189

0.075 mg/kg IV twice daily on Days 1 through 5

DRUG

0.15mg/kg TT301MW189

0.15 mg/kg IV twice daily on Days 1 through 5

DRUG

0.25mg/kg TT301/MW189

0.25 mg/kg IV twice daily on Days 1 through 5

DRUG

0.30mg/kg TT301/MW189

0.30 mg/kg IV twice daily on Days 1 through 5

DRUG

Placebo

0.9% sodium chloride

Trial Locations (1)

27710

Duke Clinical Research Unit 40 Duke Medicine Circle, Durham

Sponsors
All Listed Sponsors
collaborator

Duke Clinical Research Institute

OTHER

collaborator

Alzheimer's Association

OTHER

lead

Linda Van Eldik

OTHER