672
Participants
Start Date
January 31, 2017
Primary Completion Date
December 31, 2019
Study Completion Date
December 31, 2019
The results of clarithromycin susceptibility test of H. pylori isolates
According to the results of antibiotic susceptible testing, patients who were resistant to clarithromycin were belonged into clarithromycin resistance group.Patients who were sensitive to clarithromycin were belonged into the 7days/10days/14days treatment groups.
Computer generated random number, randomly assigned into groups
The patients with clarithromycin sensitive. Computer generated random number,randomly assigned into 7days/10days/14days treatment groups.
The result of 13C-urea breath test of patient in 7days/10days/14days treatment groups
The intervention focused on the results from the result of 13C-urea breath test at 8 weeks after treatment in patients. All patients were taking 75mg 13C-urea and analysis with a modified isotope ratio mass spectrometer to determine the 13CO2 content.The successful treatment groups were patients with negative in 13C-urea breath tests.The failed treatment of H. pylori groups were patients with positive in 13C-urea breath tests after the standardized triple therapy treatment.
RECRUITING
Sanmen People's hospital, Taizhou
Collaborators (1)
Wenzhou Central Hospital
OTHER
The First Affiliated Hospital with Nanjing Medical University
OTHER
Taizhou Hospital
OTHER
Affiliated Wenling Hospital of Wenzhou Medical University
OTHER
Hangzhou Medical College
OTHER
Centers for Disease Control and Prevention, China
OTHER_GOV
Zhiyuan Medical Inspection Institute
OTHER
Sanmen People's Hospital
OTHER