CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)

PHASE1RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

May 8, 2017

Primary Completion Date

April 30, 2026

Study Completion Date

February 29, 2040

Conditions
Hodgkin's LymphomaNon-Hodgkin Lymphoma
Interventions
GENETIC

CAR T Cells

"Three dose levels will be evaluated based on safety data from our current study of CD30 CAR T cells. Cohorts of three to six patients will be enrolled at each dose level. Each patient will receive one infusion of CAR modified T cells according to the following dosing schedule:~Dose Level One: 2x10\^7 cells/m2. Dose Level Two: 1x10\^8 cells/m2. Dose Level Three: 2x10\^8 cells/m2."

Trial Locations (2)

77030

RECRUITING

Houston Methodist Hospital, Houston

RECRUITING

Texas Children's Hospital, Houston

All Listed Sponsors
collaborator

The Methodist Hospital Research Institute

OTHER

lead

Baylor College of Medicine

OTHER