Use of a High Density Mapping System to Complete Wide Area Circumferential Ablation of the Pulmonary Veins and Avoid Ostial Segmental Ablation

NATerminatedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

March 31, 2018

Study Completion Date

June 30, 2018

Conditions
Atrial Fibrillation
Interventions
PROCEDURE

Atrial Fibrillation Ablation

Procedure involving catheter ablation to produce pulmonary vein isolation. Pulmonary veins are isolated by assessing electrograms circumferentially around the PV using the Orion catheter.

DEVICE

Catheters used to isolate pulmonary veins

Catheters transiently inserted into body via femoral veins in order to produce pulmonary vein isolation. These catheters are the same in each arm and comprise the Orion catheter (Boston Scientific) and the Tacticath (St Jude) which are used to produce pulmonary vein isolation and which are approved for use in standard EP procedures by the relevant authorities (CE marked). It is merely the protocol by which they are used that iffers in the two arms.

PROCEDURE

Atrial Fibrillation Ablation with HD mapping to isolate PVs

Procedure involving catheter ablation to produce pulmonary vein isolation. Pulmonary veins are isolated by use of electroanatomical mapping with the Orion catheter around the sites ablation in order to target points of breakthrough.

DEVICE

Rhythmia HD mapping

Mapping activation patterns using the Rhythmia system in conjunction with the Orion catheter

Trial Locations (1)

W120HS

Hammersmith Hospital, London

Sponsors
All Listed Sponsors
collaborator

Boston Scientific Corporation

INDUSTRY

lead

Imperial College Healthcare NHS Trust

OTHER