Cognitive Biomarkers in Pediatric Brain Tumor Patients

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

October 26, 2016

Primary Completion Date

November 30, 2025

Study Completion Date

January 31, 2028

Conditions
Childhood Brain Tumor
Interventions
OTHER

Neurocognitive testing

DEVICE

rsfcMRI

The imaging protocols will be a combined version of a standard of care (SOC) protocol with a research portion. The SOC portion of the pre-surgical scans includes a 3D T2-weighted (T2w) scans and 3D pre- and post-contrast T1-weighted (T1w) images, both at high resolution (1.0 mm3) for use in the intraoperative navigation system. This scan also includes a DTI portion for definition of fiber bundles of interest. The SOC portion of the post-surgical scans includes transverse FLAIR and post-contrast T1w images in all 3 planes. The research portion of the scan will be identical at all 3 time points and include 15 min of rsfcMRI during which the non-sedated subjects will be asked to stay still and awake while looking at a fixation cross

Trial Locations (1)

63110

RECRUITING

Washington University School of Medicine, St Louis

All Listed Sponsors
collaborator

Children's Discovery Institute

OTHER

collaborator

Neurosurgery Research & Education Foundation

UNKNOWN

collaborator

The Andrew McDonough B+ Foundation

OTHER

lead

Washington University School of Medicine

OTHER