NCT02912312View on ClinicalTrials.gov

Hypofractionated vs. Conventional Regional Nodal Radiation Therapy for Patients With Invasive Breast Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

805

Participants

Timeline

Start Date

February 23, 2017

Primary Completion Date

February 28, 2030

Study Completion Date

February 28, 2031

Conditions
Invasive Breast CarcinomaStage I Breast Cancer AJCC v7Stage IA Breast Cancer AJCC v7Stage IB Breast Cancer AJCC v7Stage II Breast Cancer AJCC v6 and v7Stage IIA Breast Cancer AJCC v6 and v7Stage IIB Breast Cancer AJCC v6 and v7Stage IIIA Breast Cancer AJCC v7Stage IIIC Breast Cancer AJCC v7
Interventions
RADIATION

Hypofractionated Radiation Therapy

Undergo hypofractionated RNI

OTHER

Laboratory Biomarker Analysis

Correlative studies

OTHER

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

RADIATION

Radiation Therapy

Undergo standard RNI

Trial Locations (12)

32207

Baptist - MD Anderson Cancer Center, Jacksonville

32806

Orlando Health Cancer Institute, Orlando

43215

Ohio Health, Columbus

46219

Community MD Anderson Cancer Center East, Indianapolis

46227

Community MD Anderson Cancer Center South, Indianapolis

49625

Community MD Anderson Cancer Center North, Indianapolis

77030

M D Anderson Cancer Center, Houston

78229

UT Health San Antonio - MD Anderson Cancer Center, San Antonio

80631

MD Anderson Cancer Center (Banner)- Northern Colorado, Greeley

85234

MD Anderson Cancer Center (Banner), Gilbert

92121

Scripps- MD Anderson Cancer, San Diego

08103

Cooper Hospital University Medical Center, Camden

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER