Changes in Skin Autoflouresence Following Weight Loss and Maintenance Using Liraglutide in Knee Osteoarthritis

PHASE4CompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

February 28, 2019

Study Completion Date

March 31, 2019

Conditions
Osteoarthritis, Knee
Interventions
DRUG

Liraglutide 3 mg (Saxenda)

Dose escalation scheme: Initial dosage of 0.6 mg per day, escalated bi-weekly by 0.6 mg to 3 mg per day over a total of 8 weeks

DRUG

Liraglutide 3 mg placebo

Dose escalation scheme: Initial dosage of a 0.6 mg drug equivalent volume per day, escalated bi-weekly by an 0.6 mg drug equivalent volume per day to a 3 mg drug equivalent volume per day over a total of 8 weeks.

Trial Locations (1)

2000

Department of Rheumatology, Frederiksberg

Sponsors
All Listed Sponsors
lead

Parker Research Institute

OTHER