Chidamide in Combination With ART for Reactivation of the Latent HIV-1 Reservoir

PHASE2/PHASE3UnknownINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

November 29, 2016

Primary Completion Date

August 31, 2018

Study Completion Date

December 31, 2018

Conditions
Chronic HIV Infections
Interventions
DRUG

ART plus Chidamide

Chidamide will be administrated 10mg each time, twice a week, interval not less than 3 days for 12 weeks.Antiretroviral therapy will be kept during entire study.

DRUG

ART plus Placebo

Placebo will be administrated 10mg each time, twice a week, interval not less than 3 days for 12 weeks.Antiretroviral therapy will be kept during entire study.

Trial Locations (3)

710038

Department of Infectious Diseases, Tangdu Hospital, The Fourth Military Medical University, Xi'an

Unknown

The First Affiliated Hospital of Guangxi Medical University, Nanning

Zhejiang University, Hangzhou

Sponsors
All Listed Sponsors
collaborator

Chipscreen Biosciences, Ltd.

INDUSTRY

collaborator

Zhejiang University

OTHER

collaborator

First Affiliated Hospital of Guangxi Medical University

OTHER

lead

Tang-Du Hospital

OTHER