Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 24, 2016

Primary Completion Date

March 13, 2017

Study Completion Date

March 13, 2017

Conditions
NeoplasmsNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeBronchial NeoplasmsLung NeoplasmsRespiratory Tract NeoplasmsThoracic NeoplasmsDigestive System NeoplasmsEndocrine Gland NeoplasmsCarcinoma, Non-Small-Cell LungLung DiseasesBreast NeoplasmsBreast DiseasesRenal NeoplasmSolid Tumors
Interventions
DRUG

Entinostat

Single, supratherapeutic dose of entinostat given orally.

DRUG

Placebo

Single dose of placebo-matching entinostat (containing inactive ingredients matching the appearance of the active product).

Trial Locations (1)

78229

The START Center for Cancer Care, San Antonio

Sponsors
All Listed Sponsors
lead

Syndax Pharmaceuticals

INDUSTRY