40
Participants
Start Date
March 31, 2015
Primary Completion Date
January 31, 2017
Study Completion Date
January 31, 2018
Diurnal Variation Group
This intervention occurs over one 24-hour period. Eligible participants will be required to be admitted into a supervised environment for 24-hours arriving no later than 0730. Blood draws will then be taken every 4 hours (0800, 1200, 1600, 2000, 2400 and 0400). Care will be taken to ensure the total blood draws (including the screening visit) stay within Red Cross Guidelines (less than 500 ml every 8 weeks).
External Stress Group
"2 visits will be required, each lasting approximately 2.5 hours in the afternoon.~At both visits participants will rest quietly for 15 minutes, then have 3 blood draws and 4 saliva samples over approximately one hour. Participants will also be required to complete short questionnaires about their mood and experience.~At the second visit, participants will also complete some thinking and talking tasks. In addition the autonomic nervous system of the participant's will be monitored throughout the visit."
Division of Infectious Diseases, Milwaukee
Osher Center, University of California San Francisco, San Francisco
University of California, San Francisco
OTHER
University of Melbourne
OTHER