Clinical Study of Chinese Medicine Plus Targeted Therapy Maintenance in Advanced Pulmonary Adenocarcinoma

PHASE3CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

March 31, 2013

Primary Completion Date

December 30, 2016

Study Completion Date

June 1, 2017

Conditions
Cancer
Interventions
DRUG

YiQiFang

"Prescriptions formulated into TCM granules origin from Professor Liu Jia-xiang in Longhua hospital. Package of granules is made into three types with functions such as benefiting Qi, benefiting Yin and detoxication recipe.~YiQiFang: Patients with Qi deficiency syndrome are administered two packages of each benefiting Qi and detoxication recipe, four packages, twice a day, until progression or unacceptable."

DRUG

YangYinFang

"Prescriptions formulated into TCM granules origin from Professor Liu Jia-xiang in Longhua hospital. Package of granules is made into three types with functions such as benefiting Qi, benefiting Yin and detoxication recipe.~YangYinFang: Patients with Yin deficiency syndrome are administered two packages of each benefiting Yin and detoxication recipe, four packages, twice a day, until progression or unacceptable."

DRUG

YiQiYangYinFang

"Prescriptions formulated into TCM granules origin from Professor Liu Jia-xiang in Longhua hospital. Package of granules is made into three types with functions such as benefiting Qi, benefiting Yin and detoxication recipe.~YiQiYangYinFang: Patients with Qi and Yin deficiency syndrome are administered one package of each benefiting Qi and benefiting Yin and two packages of detoxication recipe, four packages, twice a day, until progression or unacceptable."

DRUG

placebo granules

Oral granules, which the taste and smell are similar to experimental TCM granules, has no therapeutic effect, four packages, twice a day, until progression or unacceptable.

DRUG

Erlotinib®

"Erlotinib®,tarceva, 150 mg oral once a day until progression or unacceptable toxicity develops."

DRUG

Gefitinib®

"Gefitinib®,Iressa, 250 mg oral once a day until progression or unacceptable toxicity develops."

DRUG

Icotinib®

"Icotinib®,Conmana 125 mg oral three times a day until progression or unacceptable toxicity develops."

All Listed Sponsors
collaborator

Shanghai Chest Hospital

OTHER

collaborator

Shanghai Pulmonary Hospital, Shanghai, China

OTHER

lead

Shanghai University of Traditional Chinese Medicine

OTHER

NCT02889692 - Clinical Study of Chinese Medicine Plus Targeted Therapy Maintenance in Advanced Pulmonary Adenocarcinoma | Biotech Hunter | Biotech Hunter