23
Participants
Start Date
March 31, 2013
Primary Completion Date
December 30, 2016
Study Completion Date
June 1, 2017
YiQiFang
"Prescriptions formulated into TCM granules origin from Professor Liu Jia-xiang in Longhua hospital. Package of granules is made into three types with functions such as benefiting Qi, benefiting Yin and detoxication recipe.~YiQiFang: Patients with Qi deficiency syndrome are administered two packages of each benefiting Qi and detoxication recipe, four packages, twice a day, until progression or unacceptable."
YangYinFang
"Prescriptions formulated into TCM granules origin from Professor Liu Jia-xiang in Longhua hospital. Package of granules is made into three types with functions such as benefiting Qi, benefiting Yin and detoxication recipe.~YangYinFang: Patients with Yin deficiency syndrome are administered two packages of each benefiting Yin and detoxication recipe, four packages, twice a day, until progression or unacceptable."
YiQiYangYinFang
"Prescriptions formulated into TCM granules origin from Professor Liu Jia-xiang in Longhua hospital. Package of granules is made into three types with functions such as benefiting Qi, benefiting Yin and detoxication recipe.~YiQiYangYinFang: Patients with Qi and Yin deficiency syndrome are administered one package of each benefiting Qi and benefiting Yin and two packages of detoxication recipe, four packages, twice a day, until progression or unacceptable."
placebo granules
Oral granules, which the taste and smell are similar to experimental TCM granules, has no therapeutic effect, four packages, twice a day, until progression or unacceptable.
Erlotinib®
"Erlotinib®,tarceva, 150 mg oral once a day until progression or unacceptable toxicity develops."
Gefitinib®
"Gefitinib®,Iressa, 250 mg oral once a day until progression or unacceptable toxicity develops."
Icotinib®
"Icotinib®,Conmana 125 mg oral three times a day until progression or unacceptable toxicity develops."
Shanghai Chest Hospital
OTHER
Shanghai Pulmonary Hospital, Shanghai, China
OTHER
Shanghai University of Traditional Chinese Medicine
OTHER