Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC

PHASE2CompletedINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

February 28, 2014

Primary Completion Date

August 31, 2022

Study Completion Date

August 31, 2022

Conditions
High-Grade Upper Tract Urothelial Carcinoma
Interventions
PROCEDURE

Radical nephroureterectomy

Radical nephroureterectomy (RNU) with an ipsilateral bladder cuff

PROCEDURE

Distal ureterectomy

Distal ureterectomy.

DRUG

Neoadjuvant Chemotherapy

Gemcitabine, 1250mg/m2, d1 d8, Cisplatin, 75mg/m2, d1-d3, 21d, 2-4 cycles.

Trial Locations (1)

410008

Xiangya Hospital of Central South Univeristy, Changsha

All Listed Sponsors
collaborator

Central South University

OTHER

collaborator

The Third Xiangya Hospital of Central South University

OTHER

collaborator

Hunan Cancer Hospital

OTHER

collaborator

Hunan Provincial People's Hospital

OTHER

lead

Xiangya Hospital of Central South University

OTHER

NCT02876861 - Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC | Biotech Hunter | Biotech Hunter