23
Participants
Start Date
January 24, 2018
Primary Completion Date
December 31, 2022
Study Completion Date
December 31, 2025
Ruxolitinib
15 or 20 mg, twice daily by mouth. The run-in part of ruxolitinib lasts 7 days; The treatment of ruxolitinib part lasts 12 weeks.
Paclitaxel
80 mg/m2, IV (in the vein) weekly for 12 weeks.
Doxorubicin
60 mg/m2, IV (in the vein) every 14 days for 4 doses.
Cyclophosphamide
600 mg/m2, IV (in the vein) every 14 days for 4 doses.
Duke University Medical Center, Durham
Mayo Clinic, Rochester
MD Anderson Cancer Center, Houston
Dana-Farber Cancer Institute, Boston
Collaborators (1)
Incyte Corporation
INDUSTRY
Dana-Farber Cancer Institute
OTHER