A Phase II Study Of Nivolumab/ Bevacizumab/Rucaparib

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

November 10, 2016

Primary Completion Date

February 28, 2025

Study Completion Date

January 31, 2027

Conditions
Peritoneal CancerOvarian CancerFallopian Tube Cancer
Interventions
DRUG

Bevacizumab

"* Bevacizumab will be given intravenously at a pre-determined dosage~* One dose reduction will be allowed for Bevacizumab"

DRUG

Nivolumab

"* Nivolumab injection is to be administered as an IV infusion at a pre-determined dosage.~* No dose reductions or escalations will be allowed for Nivolumab"

DRUG

Rucaparib

"* Rucaparib will be taken orally twice daily on days 1-14 at a pre-determined dosage.~* Up to three dose reductions will be allowed for Rucaparib (depending on cohort)."

Trial Locations (3)

02114

Massachusetts General Hospital, Boston

02115

Dana Farber Cancer Institute, Boston

02215

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

collaborator

Clovis Oncology, Inc.

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER