11
Participants
Start Date
January 31, 2017
Primary Completion Date
July 31, 2017
Study Completion Date
July 31, 2017
Cognitive Behavioral Counseling
Participants will receive five cognitive-behavioral counseling sessions designed to improve rates of smoking cessation, enhance relapse prevention, and increase physical activity.
Mobile Contingency Management
Participants will be asked to provide video recordings of themselves taking carbon monoxide readings in order to confirm smoking abstinence. They will also be asked to wear a fitness tracker to monitor physical activity (i.e., steps walked). Participants are provided monetary reward for videos that suggest smoking abstinence, and for fitness tracker readings that suggest increased physical activity.
Bupropion
All participants who are medically eligible will be prescribed bupropion, which they will start two weeks prior to their quit day. Dosage will be 150 mg/daily for days 1-7 and 300 mg/daily (administered in two daily doses) until the 6-month follow-up.
Transdermal nicotine patch
Initiated at smoking quit date; 7 mg to 21 mg patch depending on amount smoked by participant
Nicotine polacrilex
Nicotine gum will be initiated at smoking quit date; 4 mg dose administered as needed
Nicotine lozenge
Nicotine lozenge will be initiated at smoking quit date; 4 mg dose administered as needed
Duke University Medical Center, Durham
Lead Sponsor
Duke University
OTHER