Study of Immune Checkpoint Inhibition With Radiation Therapy in Unresectable, Non-metastatic Pancreatic Cancer

PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

August 7, 2016

Primary Completion Date

March 4, 2019

Study Completion Date

March 4, 2019

Conditions
Pancreatic Cancer
Interventions
DRUG

MEDI4736

anti-PD-L1 human monoclonal antibody

DRUG

Tremelimumab

anti-CTLA4 human monoclonal antibody

RADIATION

Stereotactic Body Radiation Therapy (SBRT)

Stereotactic body radiation therapy (SBRT) will be administered at the standard dose of 6 Gy daily for 5 days.

Trial Locations (3)

10016

New York University School of Medicine, New York

10461

Montefiore Medical Center, The Bronx

20007

Georgetown University Medical Center, Washington D.C.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

NYU Langone Health

OTHER