93
Participants
Start Date
August 22, 2016
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Gene panel sequencing of tumor specimens
Archival or biopsied tumor specimens will undergo gene panel sequencing to identify subgroups with targetable genetic (ALK, MAPK pathway, Metabolic-related genes) and/or immunologic (tumor associated macrophage infiltration, PD-L1 expression) biomarkers in neuroblastoma. A clinical report will be provided to subjects/subject physician detailing observed mutations and identified NBL subgroups and information on clinical trials that best match them. Subjects will be followed and data collected on treatments administered for one year after receipt of clinical report.
University of North Carolina, Chapel Hill
Children's Healthcare of Atlanta, Atlanta
C.S Mott Children's Hospital, Ann Arbor
Children's Memorial Hospital - Chicago, Chicago
Cook Children's Healthcare System, Fort Worth
Children Hospital of Colorado, Aurora
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco
Children's Hospital and Regional Medical Center - Seattle, Seattle
Children's Hospital Los Angeles, Los Angeles
Childrens Hospital Boston, Dana-Farber Cancer Institute., Boston
Cincinnati Children's Hospital Medical Center, Cincinnati
Children's Hospital Los Angeles
OTHER
The Evan Foundation
OTHER
St. Baldrick's Foundation
OTHER
Press On Fund
UNKNOWN
Rising Tide Foundation
OTHER
New Approaches to Neuroblastoma Therapy Consortium
OTHER