Neuroblastoma Precision Trial

Active, not recruitingOBSERVATIONAL
Enrollment

93

Participants

Timeline

Start Date

August 22, 2016

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Neuroblastoma
Interventions
OTHER

Gene panel sequencing of tumor specimens

Archival or biopsied tumor specimens will undergo gene panel sequencing to identify subgroups with targetable genetic (ALK, MAPK pathway, Metabolic-related genes) and/or immunologic (tumor associated macrophage infiltration, PD-L1 expression) biomarkers in neuroblastoma. A clinical report will be provided to subjects/subject physician detailing observed mutations and identified NBL subgroups and information on clinical trials that best match them. Subjects will be followed and data collected on treatments administered for one year after receipt of clinical report.

Trial Locations (11)

27599

University of North Carolina, Chapel Hill

30322

Children's Healthcare of Atlanta, Atlanta

48109

C.S Mott Children's Hospital, Ann Arbor

60614

Children's Memorial Hospital - Chicago, Chicago

76104

Cook Children's Healthcare System, Fort Worth

80045

Children Hospital of Colorado, Aurora

94143

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

98105

Children's Hospital and Regional Medical Center - Seattle, Seattle

90027-0700

Children's Hospital Los Angeles, Los Angeles

02115

Childrens Hospital Boston, Dana-Farber Cancer Institute., Boston

45229-3039

Cincinnati Children's Hospital Medical Center, Cincinnati

All Listed Sponsors
collaborator

Children's Hospital Los Angeles

OTHER

collaborator

The Evan Foundation

OTHER

collaborator

St. Baldrick's Foundation

OTHER

collaborator

Press On Fund

UNKNOWN

collaborator

Rising Tide Foundation

OTHER

lead

New Approaches to Neuroblastoma Therapy Consortium

OTHER

NCT02868268 - Neuroblastoma Precision Trial | Biotech Hunter | Biotech Hunter