Impact of Combined Behavioral Interventions on Cognitive Outcomes in MCI

NACompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

September 30, 2014

Primary Completion Date

October 31, 2018

Study Completion Date

October 31, 2018

Conditions
Mild Cognitive Impairment
Interventions
BEHAVIORAL

Walking Intervention

The walking intervention will begin following baseline assessments and will be continued for 12 weeks. Participants will be given a pedometer to use daily and log their daily steps, with an identified goal of increasing step counts by 3000 steps a day over the course of the intervention. After obtaining a week long baseline step count, individuals in the intervention group will progressively increase their step counts by 100 steps daily each week for the first three weeks, by 200 steps daily for weeks four through six, by 300 steps daily for weeks seven through nine, and by 400 steps daily for weeks ten through twelve. Mean baseline step counts for sedentary older adults in our pilot work were 4150 per day; therefore, most participants will almost double their daily activity by the end of the intervention.

BEHAVIORAL

Cognitive Training Intervention

In the CT condition, participants will use Brain HQ, a computer cognitive training program (Posit Science Corporation, San Francisco, CA), shown to be well tolerated by older adults with positive short- and long-term cognitive outcomes. Participants will use the program 60 minutes/day, 5 days/week for 12 weeks. If participants do not have a home computer/internet access, they can complete the modules at another location such as a public library, senior center, or at the MARC, but training will still be self-directed.

BEHAVIORAL

Combined Intervention

The combined condition will concurrently follow both the walking and the CT programs as described above.

Trial Locations (1)

92037

UCSD, La Jolla

All Listed Sponsors
collaborator

Alzheimer's Association

OTHER

lead

University of California, San Diego

OTHER

NCT02864069 - Impact of Combined Behavioral Interventions on Cognitive Outcomes in MCI | Biotech Hunter | Biotech Hunter