Clinical Trial of GX-I7 in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 11, 2016

Primary Completion Date

January 20, 2017

Study Completion Date

June 2, 2018

Conditions
Healthy
Interventions
DRUG

GX-I7

Interleukin-7 (IL-7) is T cell growth factor that can be used for treating lymphopenia patients. GX-I7 is a protein drug recombining human IL-7 and hybrid Fc (hyFc). HyFc made by Genexine is composed of hinge-CH2 region of Immunoglobulin D (IgD) and CH2-CH3 region of Immunoglobulin G4 (IgG4). The recombined region is not exposed and each region's characteristics can reduce immunogenicity and improve the efficacy of drug. Consequently, it will be able to treat the patients with lymphopenia in effective ways.

DRUG

Placebo

This is the placebo of GX-I7 described above.

Trial Locations (1)

110-744

Seoul National University Hospital, Seoul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Genexine, Inc.

INDUSTRY

NCT02860715 - Clinical Trial of GX-I7 in Healthy Volunteers | Biotech Hunter | Biotech Hunter