Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesothelioma

PHASE2CompletedINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

June 30, 2018

Study Completion Date

May 31, 2019

Conditions
MesotheliomaBAP1 Loss of Function
Interventions
DRUG

Tazemetostat

Tazemetostat (EPZ-6438) is a selective small molecule inhibitor of the histone-lysine methyltransferase EZH2 gene.

Trial Locations (16)

10065

Memorial Sloan Kettering Cancer Center, New York

33076

Institut Bergonie, Bordeaux

55905

Mayo Clinic - Rochester, Rochester

59037

CHRU de Lille, Lille

90025

University of California, Los Angeles, Los Angeles

90301

City of Hope National Medical Center, Los Angeles

94143

University of California San Francisco, San Francisco

94805

Institut Gustave Roussy, Villejuif

02114

Massachusetts General Hospital, Boston

02215

Dana-Farber Cancer Institute, Boston

LE1 9HN

University of Leicester & Leicester University Hospitals, Leicester

EC1M 6BQ

St. Bartholomew's Hospital, London

NW1 2PG

University College Hospital, London

SW3 6JJ

Royal Marsden Hospital - Chelsea, London

M23 9LT

University Hospital of South Manchester, Manchester

SM2 5PT

Royal Marsden Hospital - Surrey, Sutton

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Epizyme, Inc.

INDUSTRY

NCT02860286 - Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesothelioma | Biotech Hunter | Biotech Hunter